Mateos M-V, Blad J, Bringhen S, Ocio EM, Efebera Y, Pour L, Gay F, Sonneveld P, Gullbo J et al (2020) Melflufen: a peptidedrug conjugate for the treatment of multiple myeloma
Areas with thinner skin, such as around the eyes or on the backs of hands, may show improvement earlier than areas with more significant laxity
Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function
It relies heavily on glutathione to bind to toxins and metabolic waste, making them water-soluble so they can be excreted
10.1038/tp.2012.95 41